During menstruation (do not apply to abdomen), pregnant or breastfeeding, infections and diseases of the, high or unbalanced cholesterol, thyroid disease and other hormonal disorders, any chronic diseases, immune diseases, heart disease or pacemakers, autoimmune diseases, HIV or AIDS, cancer that is currently being treated, severe high blood pressure or circulation problems, liver or kidney disease, treatment with anti-inflammatory, anticoagulants, antibiotics, or you are under the age of 18.